Extramammary Paget disease - clinical appearance, pathogenesis, management

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Extramammary Paget Disease: Minimal Surgical Therapy

BACKGROUND Extramammary Paget disease (EMPD) is an uncommon malignant neoplasm affecting apocrine gland-bearing skin which usually occurs in the anogenital area of patients older than 50 years. Although Mohs micrographic surgery (MMS) is recommended for the treatment of EMPD, wide local excision has also been performed by many other surgeons including dermatosurgeons. However, the extent of an ...

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Aggressive clinical course of extramammary Paget disease after radiotherapy

Extramammary Paget disease (EMPD) is a rare disease, especially in Asian populations. Surgical resection is considered the primary treatment option. Recently, radiotherapy has been suggested as an EMPD treatment, either as an alternative to surgical resection or in combination with surgical resection. This report reviewed a patient with EMPD who was treated with wide excision of the EMPD site f...

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[Extramammary Paget disease treated with 5% imiquimod cream].

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Extramammary Paget disease: a report of 10 cases.

Extramammary Paget disease (EMPD) is a very rare form of intraepithelial adenocarcinoma. We report the cases of EMPD diagnosed in a referral hospital over a 5-year period from 2009 to 2013. Ten cases of EMPD were diagnosed in 4 men and 6 women aged between 50 and 79 years. Erroneous clinical diagnoses led to diagnostic delays of 1 to 5 years in all cases. Six patients had in situ lesions and de...

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Extramammary Paget Disease of the Vulva - Case Report.

Extramammary Paget disease (EPD) is a rare malign neoplasm that may affect the vulva and has manifestations common to benign diseases such as itching, pain and eczema. This leads to delay in diagnosis and consequent worse prognosis. The definitive diagnosis is obtained by biopsy of the vulva, which shows Paget cells. The treatment of choice is wide excision with margins, which leads to sequelae...

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ژورنال

عنوان ژورنال: JDDG: Journal der Deutschen Dermatologischen Gesellschaft

سال: 2011

ISSN: 1610-0379

DOI: 10.1111/j.1610-0387.2010.07581.x